GSM5102857: C3H/HeJ AA mice - JAK2i #1; Mus musculus; RNA-Seq - SRA

SRX10157458: GSM5102857: C3H/HeJ AA mice - JAK2i #1; Mus musculus; RNA-Seq
1 ILLUMINA (Illumina HiSeq 4000) run: 26.8M spots, 8G bases, 3.2Gb downloads

Submitted by: NCBI (GEO)

Study: RNA-seq of C3H/HeJ AA mice skin biopsies treated with JAK-selective inhibitors

PRJNA704387 • SRP307763 • All experiments • All runs

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To define the molecular response to JAKi treatment, we performed RNA-seq analysis on a series of skin biopsies taken before and after systemic treatment with INCB039110 (JAK1i), CEP-33779 (JAK2i), PF-06651600 (JAK3i), ruxolitinib (JAK1/2i), tofacitinib (pan-JAKi) or vehicle control. Overall design: mRNA profiles to JAKi treatment of C3H/HeJ AA mice.

Sample: C3H/HeJ AA mice - JAK2i #1

SAMN18039476 • SRS8309409 • All experiments • All runs

Organism: Mus musculus

Library:

Instrument: Illumina HiSeq 4000

Strategy: RNA-Seq

Source: TRANSCRIPTOMIC

Selection: cDNA

Layout: PAIRED

Construction protocol: Total cellular RNA was extracted using RNeasy Plus Micro Kit (catalog 74034, QIAGEN) from skin homogenates of indicated JAKi treated mice or control. RNA quality and quantity were determined using an Agilent BioAnalyzer (Agilent Technologies). Libraries were constructed, pooled and sequenced on an Illumina HiSeq Mid Output run to generate 16-23 million 75-bp paired-end reads per sample at GENEWIZ (South Plainfield, NJ, GENEWIZ).

Experiment attributes:

GEO Accession: GSM5102857

Links:

NCBI link: NCBI Entrez (gds)

Runs: 1 run, 26.8M spots, 8G bases, 3.2Gb

Run	# of Spots	# of Bases	Size	Published
SRR13771781	26,793,868	8G	3.2Gb	2021-02-25

ID:: 13285034

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Sequence Read Archive

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